Synthesis of hydrofluoroethers (HFEs) as alternatives to CFCs
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Author(s)
Abstract
A facile synthetic route for the preparation of a series of hydrofluoroethers (HFEs) was developed. This route was based on two key reactions. The first reaction involved the alcoholysis of various fluoroalcohols with p-toluenesulfonyl chloride in a sodium hydroxide solution, while the second involved the Williamson ether syntheses of the desired HFEs from the corresponding tosylates using sodium methoxide in methanol. As a result, a range of HFEs were synthesized using this mild and efficient method.
Keywords
hydrofluoroethers • alcoholysis • Williamson ether synthesis
Cite this paper
Wei Li, Zhikai Guo, Hengdao Quan,
Synthesis of hydrofluoroethers (HFEs) as alternatives to CFCs
, SCIREA Journal of Chemistry.
Volume 3, Issue 2, April 2018 | PP. 13-24.
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